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2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

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  Post Date: Jun 25,2015
  Expiry Date: Jun 24,2016
  Detailed Description: Cas No. :73231-34-2 Payment Method: t/t
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
CAS: 73231-34-2
MF: C12H14Cl2FNO4S
MW: 358.21
mp 153 °C
storage temp. 0-6°C
form solid

Chemical Properties White Crystalline Powder
Usage Fluorinated derivative of thiamphenicol. Inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. An antibacterial

Usage Antibacterial;Protein synthesis inhibitor

Usage Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.

Usage Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations.

Antibiotics, and produce broad-spectrum antibacterial effect by inhibiting peptide transferase activity, broad antibacterial spectrum, including Gram-positive, Gram -negative bacteria
And Mycoplasma

  CAS Registry Number:

73231-34-2

  Synonyms: ;2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide;Florfeniol;Flofenicol;2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide;2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide;
  Molecular Formula: C12H14Cl2FNO4S
  Molecular Weight: 358.2133
  Molecular Structure: 73231-34-2 Florfenicol

  Company: Hulumimi Pharmaceuticals     [ China ]        
  Contact: Toni Zhong
  Tel: 027-50756080
  Fax: 0086-27-88048077-794
  Email: toni@ycgmp.com
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