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2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
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Post Date: | Jun 25,2015 |
Expiry Date: | Jun 24,2016 |
Detailed Description: |
Cas No. :73231-34-2
Payment Method: t/t 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide CAS: 73231-34-2 MF: C12H14Cl2FNO4S MW: 358.21 mp 153 °C storage temp. 0-6°C form solid Chemical Properties White Crystalline Powder Usage Fluorinated derivative of thiamphenicol. Inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. An antibacterial Usage Antibacterial;Protein synthesis inhibitor Usage Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial. Usage Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations. Antibiotics, and produce broad-spectrum antibacterial effect by inhibiting peptide transferase activity, broad antibacterial spectrum, including Gram-positive, Gram -negative bacteria And Mycoplasma |
CAS Registry Number: | 73231-34-2 |
Synonyms: | ;2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide;Florfeniol;Flofenicol;2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide;2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide; |
Molecular Formula: | C12H14Cl2FNO4S |
Molecular Weight: | 358.2133 |
Molecular Structure: |
Company: | Hulumimi Pharmaceuticals [ China ] |
Contact: | Toni Zhong |
Tel: | 027-50756080 |
Fax: | 0086-27-88048077-794 |
Email: | toni@ycgmp.com |
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